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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKA
All Species:
35.76
Human Site:
S398
Identified Species:
78.67
UniProt:
P23677
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23677
NP_002211.1
461
51009
S398
R
R
H
E
V
I
G
S
S
L
L
F
V
H
D
Chimpanzee
Pan troglodytes
XP_001149577
401
45057
S338
R
R
H
E
V
I
G
S
S
L
L
F
V
H
D
Rhesus Macaque
Macaca mulatta
XP_001099176
645
70639
S582
R
R
H
E
V
I
G
S
S
L
L
F
V
H
D
Dog
Lupus familis
XP_544631
632
69191
S569
R
R
H
E
V
I
G
S
S
L
L
F
V
H
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R071
459
50916
S396
R
R
H
E
V
I
G
S
S
L
L
F
V
H
D
Rat
Rattus norvegicus
P17105
459
50852
S396
R
R
H
E
V
I
G
S
S
L
L
F
V
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990212
452
51079
S389
K
R
H
E
V
V
G
S
S
L
L
F
V
H
D
Frog
Xenopus laevis
NP_001088157
516
58252
S453
Q
S
H
E
V
V
G
S
S
L
L
F
V
H
D
Zebra Danio
Brachydanio rerio
Q5TZ07
288
31266
I240
L
V
L
L
W
A
T
I
V
G
F
S
R
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
S572
Q
T
H
E
V
I
G
S
S
L
L
F
V
H
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
F308
A
C
V
W
M
I
D
F
G
K
T
T
P
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
70.5
68.6
N.A.
93.2
93.4
N.A.
N.A.
64.6
44.5
21
N.A.
37.6
N.A.
N.A.
42.7
Protein Similarity:
100
86.5
70.8
69.7
N.A.
96
96
N.A.
N.A.
74.6
57.9
32.9
N.A.
46.6
N.A.
N.A.
53.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
80
0
N.A.
86.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
0
N.A.
93.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
82
% D
% Glu:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
82
0
0
0
% F
% Gly:
0
0
0
0
0
0
82
0
10
10
0
0
0
0
0
% G
% His:
0
0
82
0
0
0
0
0
0
0
0
0
0
82
0
% H
% Ile:
0
0
0
0
0
73
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
10
10
0
0
0
0
0
82
82
0
0
10
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
55
64
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
0
0
0
0
0
82
82
0
0
10
0
0
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
10
10
0
0
0
% T
% Val:
0
10
10
0
82
19
0
0
10
0
0
0
82
10
0
% V
% Trp:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _